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Literature summary extracted from

  • Duckett, S.K.; Pratt, S.L.; Pavan, E.
    Corn oil or corn grain supplementation to steers grazing endophyte-free tall fescue. II. Effects on subcutaneous fatty acid content and lipogenic gene expression (2009), J. Anim. Sci., 87, 1120-1128.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.85 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.85 subcutaneous adipose tissue
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.85 acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+
-
 Bos taurus palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.85 FASN
-
 Bos taurus
2.3.1.85 fatty acid synthase
-
 Bos taurus

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.85 NADPH
-
 Bos taurus

Expression

EC Number Organism Comment Expression
2.3.1.85 Bos taurus relative FASN mRNA expression is upregulated by 9 and 5fold, respectively, for high-concentrate diet (85% concentrate: 15% roughage) and diet on endophyte-free tall fescue pastures with corn grain supplement compared with pasture diet, grain feeding upregulates FASN mRNA expression up

General Information

EC Number General Information Comment Organism
2.3.1.85 physiological function fatty acid synthase is a key enzyme regulating de novo fatty acid synthesis Bos taurus